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However, in practice, doseresponse patterns are significantly complicated due to many other interactions with (i) multiple targets (receptors) of different affinities to the active compound, (ii) other regulatory proteins or mediators in the networks involved in the adaptive stress response, (iii) feedback down regulations in the molecular signaling pathways, and/or (iv) metabolic transformation of active ligands into metabolites, a secondary ligand, which have different affinities to various receptors of the adaptive stress response [69]

Collagen peptides, by promoting gut health and reducing inflammation, may enhance the production of neurotransmitters like serotonin, which is a precursor to melatonin, the hormone governing sleep cycles

BMC Endocr Disord

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