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Role of glycocalyx in SAP-associated multiple organ dysfunction The pathogenesis of SAP is complex and involves intracellular inflammatory pathways, enzyme activation, endotoxemia, and vascular endothelial damage (Table 3)

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1 Introduction Arrhythmia arises from disturbances in pulse generation, conduction, or a combination of both, potentially leading to reduced cardiac output or myocardial oxygenation, conditions that can be life-threatening