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Since semaglutide further slows gastric emptying as part of its mechanism of action, patients with pre-existing gastroparesis may experience worsening of symptoms including nausea, vomiting, bloating, and abdominal discomfort

Reconstitution is the process of adding a liquid to a lyophilised powder to create a solution

Considerations Some researchers prefer pharmaceutical-grade bacteriostatic water when consistency and standardized manufacturing are a priority

Recommended reconstitution by protocol phase This phased approach uses different vial sizes at different stages, matching the vial to the dose rather than forcing one size to work across all phases