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Are there clinical features of liver disease, myeloproliferative disorder (e.g., blood film changes of unexplained cytopenia, thrombocytosis, or leukocytosis), or another cancer (e.g., cachexia, constitutional symptoms fever, weight loss, night sweats)

Most patients start with 12 IV sessions per week for 24 weeks, then maintain with injections or monthly IVs depending on lifestyle and goals

Recommended options and typical doses include amoxicillin/clavulanate 500/125 mg three times daily, ciprofloxacin 250500 mg twice daily, doxycycline 100 mg twice daily, metronidazole 250 mg twice or three times daily, neomycin 500 mg twice daily, norfloxacin 400 mg twice daily, rifaximin 550 mg two or three times daily, tetracycline 250500 mg two to four times daily, and trimethoprim/sulfamethoxazole 160/800 mg twice daily [39]

doi: 10.47881/96.967x 228 El-SaadonyMTSaadAMElakkadHAEl-TahanAMAlshahraniOAAlshilawiMSet al