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Description

GSH GSSG

At high or chronic oxidative stress, however, the model suggests that the balance shifts towards GSSG, and removal of cysteine in the form of GSSG dominates, resulting in a decline in cysteine

The study unraveled the diminished esterase activity and heightened viscosity during DILI, which may be associated with the generation of ROS during ferroptosis [214]

It is hypothesized that H 2 S may be effective in attenuating HI injury by inhibiting reactive glial responses, synaptic modifications, and the triggering of autophagic fluxes 259 (Fig