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Although previous research has shown MAD to be highly effective in attenuating seizures, few studies have evaluated whether low plasma free carnitine plays a role in the patients state of ketosis while on the diet

In the M-ARCOL model (Mucosal Artificial Colon, an advanced in vitro system using microbiota from healthy donors), daily exposure to PEMPs for 14 days increased pathobiont Desulfovibrionaceae (Fournier et al., 2023)

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There are even cases in which the activity of PK as measured in vitro is higher than normal, but a kinetically abnormal enzyme with low in vivo activity in erythrocytes is responsible for the hemolytic anemia