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This is significant because ERK signaling is one of the master switches controlling whether damaged tissue enters a productive repair cycle or stalls in chronic inflammation

Tak PP, Firestein GS

Materials and methods Ethic statements The animal studies were carried out in strict accordance with the Detailed Rules for the Administration of Animal Experiments for Medical Research Purposes issued by the Ministry of Health of the Peoples Republic of China and were approved by the Animal Experiment Administration Committee of The Fourth Military Medical University

Instead, the copper ion becomes integrated into the molecular structure of the peptide, producing a defined coordination environment