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Therefore, proper randomized clinical trials are mandatory to reach the final verdict on the potential use of resveratrol in treating thyroid diseases

The incidence of papillomas was 74% in animals fed the control diet and 96% in mice fed a diet supplemented with methotrexate six weeks before, during, and after MCA treatment

Conversely, nicotine may exert paradoxical inhibitory effects by activating immune pathways and inducing apoptosis, such as through stimulation of immature dendritic cells via PI3K/Akt signaling and modulation of caspase-3 and Cyclin B1 expression through 7-nAChR signaling [36]