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Taken together, our study demonstrated that ferroptosis played an important role in AKI induced by FA overdose injection in mice, which could be alleviated by LA supplementation, indicating that LA may be used as a potential therapeutic approach to ameliorate AKI caused by drugs or toxicants in the clinic

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Results are presented using descriptive statistics, including the number of observations, geometric mean (for pharmacokinetic parameters only), arithmetic mean, standard deviation (SD), coefficient of variation, minimum, median and maximum for quantitative variables, and frequency for qualitative variables

Pharmacol Biochem Behav 212:173313