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[Abstract]2025 Jul:84:103693

3.1 Porphyromonas gingivalis The pathogenesis of P.g extends far beyond the confines of the oral cavity, establishing a complex Oral-Gut-Systemic Axis that underpins its role in a wide array of chronic diseases

The rate constant of hydrogen peroxide removal by glutathione is even less efficient (k ~ 1 M 1 s 1 ), suggesting that the removal of hydrogen peroxide by these two antioxidants is physiologically insignificant

It is concluded that earlier trials are of short duration, on small sample sizes and did not document patient satisfaction, duration of depigmenting effect or need for repeat treatments