Its harmless and often used in ultra-high doses
Heres what progesterone helps regulate in the male body: Balances estrogen levels: Men produce estrogen too, and when progesterone is low, estrogen can dominateleading to mood changes, weight gain, and even gynecomastia (male breast tissue growth)
First, GSTM3 downregulation led to an decrease in the number of cells in the G0/G1 phase and an increase in the number of cells in the G2/M and S phases, resulting in a higher proliferation index
A lower Firmicutes/Bacteroidetes ratio (142), reduced counts of Lactobacillaceae (143), and altered abundance of several genera have been reported (144) including Eggerthella , Klebsiella , Flavonifractor , Lachnospiraceae (145, 146), Prevotella , Eubacterium, and Rhodococcus were significantly enriched, whereas Pseudobutyrivibrio and Dialister were decreased in SLE patients (147)