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Centrally, it crosses the bloodbrain barrier to engage GLP-1 receptors in the arcuate nucleus and brainstem, modulating POMC neurons and other appetite-regulatory circuits to reduce food intake and cravings

In a 2023 clinical trial of adults with mild eczema, moisturizers containing niacinamide significantly improved: Eczema severity Itching Skin barrier function Overall quality of life Compared to standard moisturizers, niacinamide-containing creams helped reduce water loss from the skin which is a key problem in eczema

Endocrinology and Metabolism , 58(3), 219-232

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells