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We then asked whether transcription inhibition could affect post-reproductive lifespan (Fig

It plays a critical role in healthy immune function, proper detoxification, and healthy aging by directly neutralizing free radicals and maintaining the activity of vitamins C and E

Furthermore, age-related declines in ovarian reserve and BMI-related metabolic disturbances, such as increased free androgen index (FAI) and decreased sex hormone-binding globulin (SHBG), are also significant contributors to fertility challenges

Consistently, simultaneous inhibition of NOX activity and glutathione synthesis caused a notable reduction of 50.6% in tumor weight compared to no change with BSO treatment or 17.7% reduction with DPI treatment alone (Fig