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in 1988 [89]

Primary Metabolic Pathways Beta-3-Adrenergic Receptor Modulation Research in obese mice demonstrated that AOD-9604 increases expression of beta-3-adrenergic receptor RNA in adipose tissue, upregulating levels from those seen in obese animals to levels comparable with lean controls

Journal of Biomedicine and Biotechnology

Heart failure: It can affect the circulatory system and increase the risk of heart failure , a condition in which the heart is unable to pump blood effectively throughout the body