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Yusuf E, Ioan-Facsinay A, Bijsterbosch J, et al
NRF2 activity is also regulated by the availability of many binding partners, including a group of bZIP bi-directional transcription regulators named sMaf proteins (MafF, G and K) [200, 201] which, when bound to NRF2, under OS, favor its maintenance inside the nucleus thereby enhancing its activity [202]
According to the CDC, nearly 42.4% of American adults are considered obese, a figure that has steadily risen over the years
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