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Richies 2015 randomized controlled trial found that daily oral glutathione supplementation at 250 mg or 1,000 mg for six months increased GSH levels by 30-35% in red blood cells, plasma, and immune cells [15]

These include redness, swelling, warmth, bruising, and mild discomfort lasting hours to days

Researchers also investigate its function in maintaining protein thiol homeostasis, regulating enzyme activity through protein glutathionylation, and serving as a cofactor for glutathione peroxidase enzymes that neutralize lipid peroxides and hydrogen peroxide