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Our findings are in agreement with other recent observations using similar ligature models, which show a considerable increase of the distance between the cemento-enamel junction and the alveolar crest, regarded as a sign of alveolar bone loss (48, 52)

This also provides a baseline so that progress can be judged later on by repeating it every few months during the treatment

Similarly, tests for nutritional deficiency including multiple tests on vitamins and metabolites are not necessary

These characteristics are closely related to their molecular makeup and ability to retain their bioactive characteristics when incorporated into food matrices