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Kwon and Park, 2014a

However, many binders include metals and other impurities that work against the removal and/or promote toxins to move into the brain

These phenotypes are accompanied by enhanced oxidative metabolism and reduced adipose tissue inflammation, highlighting a critical role for GPR146 in promoting white adipose tissue expansion and metabolic dysfunction under conditions of nutritional excess

For example, PAE not only protects against AS but also exerts neuroprotective effects by inhibiting neuronal ferroptosis in cerebral hemorrhage (Jin et al., 2021) and serves as an antidepressant (Wei et al., 2023)