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As a result, theres local activation, differentiation of T-cells, formation of neutrophil extracellular traps (NETosis: the release of neutrophil extracellular traps containing histone and chromatin with important autoantigen), activation of natural killer cells, antigen presentation by B-cells, and antibody production

It is important to recognize that these symptoms do not exist in isolation

And I find that true with a lot of my patients as well

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