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However, this flexibility also allows GSH to penetrate deeper into the binding pocket and reach the dicopper active site

Moreover, using conditional knockout mouse models (e.g., chondrocyte-specific Trpv1 / or Slc2a1 / ), the protective effects of CAT on ferroptosis and OA progression in vivo need to be verified, combined with spatial metabolomics to analyze dynamic changes in lipid peroxidation products and antioxidant molecules in joint tissues following CAT intervention

Takebayashi A, Kimura F, Kishi Y, Ishida M, Takahashi A, Yamanaka A, et al