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It has been hypothesized that G6PD deficiency confers a selective advantage against malaria, as there is substantial overlap of G6PD deficiency prevalence in regions of historical malaria-endemicity (1), although experimental evidence supporting this malaria protection hypothesis remains mixed (26)
(etc) [DOI] [PubMed] [Google Scholar] 77.Weng Y.J., Gan H.Y
What they found: Darkening of existing nevi in 85 % of patients New nevi in 30 % Atypical features on dermatoscopy in 40 % Two cases of malignant melanoma in the followed cohort No evidence of a causal relationship, but associative correlation Why it matters: These are the most serious published safety data for Melanotan II
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