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Delayed Treatment: Vitamin B12 deficiency left untreated for longer than 3 months may cause permanent spinal cord and nerve damage

A randomized, double-blind, placebo-controlled trial in 191 older adults (75 years) with moderate vitamin B 12 deficiency (serum cobalamin concentrations of 107-210 pmol/L) without anemia provided participants with 1 mg/day of cyanocobalamin for one year (94)

This amino acid acts as a lipotropic agent which: assists in the breakdown of fats within the liver

NNMT inhibition via 5-Amino-1MQ was associated with higher NAD+ levels, thereby influencing sirtuin activation and mitochondrial function