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As a result, pSiNPs have been used extensively to deliver drugs to sensitive and hard-to-reach tissues 21 , including the delivery of small-molecule drugs to the vitreous 22,23

Namenda (memantine HCl) acts as an N-methyl-D-aspartate (NMDA) receptor antagonist designed to limit glutamate excitotoxicity and resulting neuronal damage [19,22,23]