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Transcriptional responses to Cys depletion To gain insights into the molecular responses triggered by cysteine deprivation, we conducted bulk RNA-sequencing (RNA-seq) analysis of liver (which exhibits the highest expression of Cse ), muscle (the most abundant tissue) and adipose tissue (the tissue most impacted by cysteine loss)

One of these networks is the MC system, which governs and modulates nutrient intake and energy metabolism (Williams et al., 2011

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palmeri is also linked to higher GST activity (Anderson and Gronwald Reference Anderson and Gronwald1991