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Additionally, GPX3 can interact with GSH and thioredoxin reductase, or with thioredoxin alone, to produce electrons for GSH in the presence of GSH depletion (18), which in turn protects the cells from ROS-induced deoxyribonucleic acid (DNA) and cellular damage (15)

In summary, this study examined the effects of GHRP-6 on skeletal muscle integrity under conditions of doxorubicin-induced stress

Acknowledgements Project supported by the National Natural Science Foundation of China (30672748) and Shandong Administration of Traditional Chinese Medicine (2005-070)

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