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Its primary role is immune regulation, particularly within epithelial and mucosal tissues

These are sulfur-containing molecules that catalyze the oxidative decarboxylation of alpha-keto acids, such as pyruvate and alphaketoglutarate, in the Krebs cycle

22,23 A randomized, single-blind crossover study of 26 healthy overweight adults that was published in Nutrition Journal demonstrated that, compared to a control meal, half of a Hass avocado eaten at lunch significantly reduced self-reported hunger and desire to eat and boosted satiety over the five-hour period after lunch

Therefore, we draw largely on adjacent literatures that support plausible mechanistic links, namely, neuroinflammation, gutbrain axis dysregulation, and sleep disruption, while recognising that these fields often lack consistent definitions and measures of brain fog