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Future medicinal chemistry efforts may yield next-generation compounds with enhanced properties, including improved tissue selectivity, modified pharmacokinetics, or additional mechanistic activities that complement NNMT inhibition

In cases where hypersensitivity is confirmed, desensitization protocols have been developed to allow patients to continue receiving necessary vitamin B12 supplementation safely

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By delivering vitamin B12 directly into the bloodstream, injections bypass the digestive system, ensuring optimal absorption and faster benefits