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doi: 10.1186/ar1784 207 DerryHMFagundesCPAndridgeRGlaserRMalarkeyWBKiecolt-GlaserJK

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Run slowly, over two to three hours, the patient is comfortable for the entire session

Inhibition of the Xc-system determines the decrease in GSH levels, which indirectly leads to the inactivation of GPX4 and the onset of ferroptosis ( 3+ enters cells with the assistance of transferrin and subsequently converts to Fe 2+ ( 2+ can catalyze the generation of metabolically toxic reactive oxygen species and phospholipid peroxide through the Fenton reaction, leading to cell damage or death (Figure 4)