To complement the Jadad score, the Cochrane Risk of Bias Tool (RoB 2) (Sterne et al., 2019) was also used for RCTs to provide a domain-based qualitative evaluation, assessing risks related to selection, performance, detection, attrition, and reporting
They recognize that clinical trials showed modest effects (average 2.6 kg over 12 weeks in responders), appreciate that individual response varies significantly, commit to proper nutrition and exercise foundations, and accept that the peptide is used for research purposes under medical supervision
This mitochondrial support may also contribute to healthy aging, as mitochondrial dysfunction is a hallmark of cellular aging
Its often used to address deficiencies in B12, which can lead to fatigue, anemia, and neurological symptoms