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Low fluorescent R6G signal could be detected in the cytoplasm of brain endothelial cells that received 3-PLG-dopa or 3-PLG-ibu as compared to the high signal intensive in the dual-targeted dopamine- or ibuprofen-coupled nanocarrier groups (Fig

doi: 10.3389/fphar.2023.1094435 Received 10 November 2022 Accepted 28 March 2023 Published 05 April 2023 Volume 14 - 2023 Edited by Giada Crescioli, University of Florence, Italy Reviewed by Rolando Garcia-Milian, Yale University, United States Updates Copyright 2023 Wu, Lu and Yan

Informed consent No original data are collected for this review, and hence, this study did not meet the criteria for ethical approval and formal consent is not required

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