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Common effects usually mild and often worst during titration include nausea, vomiting, diarrhea, constipation, abdominal pain, upset stomach, headache, and fatigue

Pain behaviors in these rats and the time course of mechanical hyperalgesia are similar to patients pain reports in the postoperative period [12]

doi:10.3109/10837450.2014.979944 Evidence-Base Disclosure The published evidence base for GHK-Cu consists predominantly of preclinical research animal models (often rats or mice) and in vitro cell-culture experiments