Despite early setbacks due to poor hygiene, the practice was revitalized during World War I as a lifesaving treatment
Higashikuni Y, Liu W, Numata G, Tanaka K, Fukuda D, Tanaka Y, Hirata Y, Imamura T, Takimoto E, Komuro I, Sata M
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These imparts numerous benefits over traditional ones namely Improved drug solubility, target drug delivery, prolonged drug release, reduced side effects, protection from drugs etc
