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Toxicol Sci 137:1225 Marx V (2013) Targeted proteomics

It's also theoretically possible, though not documented, that the powerful angiogenic effects of BPC-157 could be a concern in subjects with pre-existing conditions where new blood vessel growth is undesirable

This involves the increased production of reactive oxygen species (ROS) and a concomitant impairment of antioxidant defenses, such as glutathione [6, 7]