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Acquired cutis laxa: diagnostic and therapeutic considerations

Skin cell proliferation Rapamycin modulates mTOR signaling to enhance skin's natural defenses against environmental stressors like UV radiation and oxidative stress

To assess the half maximal inhibitory concentration (IC50) of FOXO4-DRI on the serum limitation-induced senescent fibroblast and the non-senescent control fibroblast, the fibroblast viability in the 2% FBS induced senescent fibroblast and 10% FBS cultured non-senescent control fibroblast with increasing concentrations of FOXO4-DRI was detected, and the cell viability curves were showed in Supplementary Fig

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