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The GPX8 gene is located on chromosome 5q11.2 and is composed of 3 exons that encode a putative GPx enzyme

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This study aimed to evaluate the roles of transcription factors nuclear factor erythroid 2-related factor 2 (NRF2) and nuclear factor-kappa B (NFKB), along with antioxidant enzymes cystathionine--lyase (CSE) and NAD(P)H dehydrogenase [quinone] 1 (NQO1) in amniotic fluid (AF) and maternal serum (MS) as potential biomarkers for prenatal screening of Down syndrome (DS)