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Description

Update on the epidemiology, genetics, and therapeutic options of hyperuricemia

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iso-ADP ribose specifically binds WWE , FHA and OB-fold domains, enabling PAR-dependent functional responses like ubiquitylation and supporting DNA damage signaling and repair

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The initial mechanical damage, the primary injury, is followed by hours, days, and weeks of secondary injury processes that often cause more functional loss than the impact itself

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It plays a major role in cellular protection against oxidative damage

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