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It can do this by reducing the expression of hTERT mRNA, but also by its - anti-estrogenic capacity

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NAD+ is a key molecule involved in all aspects of metabolism, energy production in cells

a family of kinases activated in response to stress and inflammatory stimuli that modulates multiple aspects of cardiac fibroblast function, including inflammatory responses, myofibroblast differentiation, extracellular matrix turnover and the paracrine induction of cardiomyocyte hypertrophy (Turner and Blythe, 2019)