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Furthermore, comorbidities such as hypertension (56.6%), obesity (41.7%), and diabetes (33.8%) are frequently linked to OxS and chronic inflammation in hospitalized COVID-19 patients 596

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Theoretically, yes, through two mechanisms

The metabolism of D-serine is catalyzed mainly by D-amino acid oxidase (DAAO) bonding flavin adenine dinucleotide (FAD) ( Figure 1e ) ( A study demonstrated that an important rate-limiting factor in maintaining D-serine balance in the brain is L-serine synthesis via the phosphorylation pathway, which is modeled in mice with astrocyte conditions lacking Phgdh