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Although free radical reactions are necessary for the defense mechanism of cells such as neutrophils and macrophages from immune system cells, overproduction of free radicals results in tissue damage and cell death [3]

In the acute phase, the neuroinflammatory response worsens BBB injury by degrading tight junctions and the extracellular matrix, promoting neuroglial proliferation, and activating cardiomyocytes, thereby further increasing its permeability

The results showed that the treatment was safe and well-tolerated, with no adverse events reported

They occur naturally in the body and play roles in signaling, regulation, repair, immune response, hormone modulation, and more