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Modulating the tumor microenvironment with new therapeutic nanoparticles: a promising paradigm for tumor treatment

Shorter studies (single dose or 1 month) have generally shown little to no effect [1][12]

Based on the early, limited mechanistic understanding of acetaminophen hepatotoxicity, which included reactive metabolite formation and hepatic GSH depletion [58, 59], various antidotes with the capacity to replenish hepatic GSH levels were tested

Glutathione is a naturally occurring antioxidant that helps protect cells from oxidative stress and plays an important role in normal cellular function