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This dual-pathway approach: Enhances weight loss beyond either agent alone May reduce GI side effects by lowering required GLP-1 doses Improves long-term metabolic reprogramming What the Research Says Clinical Trials on Cagrilintide: Amylin Pharma developed and tested Cagrilintide in Phase 2 trials

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The IL-6/sIL-6R fusion protein hyper-IL-6 promotes neurite outgrowth and neuron survival in cultured enteric neurons

On-treatment analysis showed weight loss of 22.7% with CagriSema, approaching the efficacy of bariatric surgery