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The slow intravenous infusion protocols used in clinical trials minimized these effects, suggesting that rapid bolus administration (which is essentially what subcutaneous injection creates) may increase the likelihood of transient side effects

Furthermore, integration of pharmacovigilance data and mechanistic understanding remains essential in guiding safe and effective drug use in clinical practice

Although this method gained some advantages, the improper dosage/use of antibiotics causes further burden, leading to antibiotic resistance than treatment itself