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151 When activated by the upstream regulators or stressors mentioned earlier, PGC-1 is transferred from the cytoplasm to the nucleus and enhances the expression of NRFs

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Secondly, we implemented a pragmatic quality filter during literature selectionexcluding studies with unclear experimental methods, insufficient sample sizes, or unvalidated outcome measures, and most of the included studies reported positive outcomes, which may reflect publication bias

You should get a G6PD blood test before receiving a high-dose Vitamin C infusion to check for glucose-6-phosphate dehydrogenase (G6PD) deficiency