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Existing questionnaires such as the Chalder Fatigue Scale or the Canadian Consensus Criteria 44 , both developed for ME/CFS, were deemed less suitable for this purpose 11
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Glutathione is a potent antioxidant composed of three amino acids: cysteine, glycine, and glutamine
Therefore, to more clearly reflect the effect of IS on plasma GSH homeostasis, it was more appropriate to use as a comparison group not healthy people characterized by a normal balance of thiols, but people at risk of stroke, which include patients with cerebral microangiopathy
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