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Laboratories studying 3-AR expression, signalling kinetics, and downstream cAMP/PKA pathway activation in adipose tissue models have incorporated this fragment as a 3-AR-interacting research compound, generating insights into the role of this receptor in adipose tissue metabolic regulation

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Atherosclerosis progression, as a chronic inflammatory mechanism, is characterized by immune system dysregulation associated with increased pro-inflammatory cytokine production, including interleukin 6 (IL-6), tumor necrosis factor- (TNF-), and IL-1 (Vinciguerra et al., 2020