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For hair growth, the relevant signaling pathways are: vascular stimulation (more blood flow to the dermal papilla), follicle repair (extending the anagen growth phase), inflammation modulation (calming the chronic low-grade inflammation that contributes to follicular miniaturization), and systemic growth signaling (IGF-1 levels that influence overall regenerative capacity)

Critical Reviews in Microbiology, 49 , 125

HIF and pulmonary vascular responses to hypoxia

In the embryonic and juvenile stages, melatonin promotes the secretion of male hormones and the development and maturation of the reproductive system by binding to MT1 and MT2 in testicular tissues (73)