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Cyanocobalamin has many approved indications (many that lead to a deficiency of cyanocobalamin through an impairment of absorption of cyanocobalamin) including: Cyanocobalamin can be administered via intramuscular (IM) or subcutaneous (SC) routes

412,413,414,415,416,417 Loss of inhibitory neurons and impairment of inhibitory neurotransmission are also observed in ASD mouse models as a result of mutations in genes such as Pten, Mecp2, Cntnap2, Shank3 and BTBR mice, which may directly lead to alterations in the balance of excitation and inhibition

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However, published results remain the conflicting and more clinical evidence is still needed to determine the clinical significance of selenium