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10 , e0004986 (2016)

Children with GSTM1 null or GSTP1 val/val genotypes had increased respiratory symptoms upon exposure to ozone [33, 57, 58]

Nevertheless, medical professionals do agree that increased intestinal permeability, or intestinal hyperpermeability, exists in certain chronic diseases ( Summary: Leaky gut, or intestinal hyperpermeability, is a phenomenon that occurs when the tight junctions of the intestinal wall become loose, allowing harmful substances to enter the bloodstream

However, Ferguson et al (1999) reported that the reaction between homocysteine thiolactone and LDL generates an LDL adduct that is more resistant to oxidative modification than native LDL