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METHYL FACTORS This nutraceutical contains five essential nutrients, in their most bioavailable forms: methyl folate (5-MTHF), active B6, active B2, active methyl B12, and betaine

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Early evidence for the potential efficacy of this route was published in 1999, where 18 patients with B12 deficiency treated exclusively with 712 days of 2 mg of sublingual cobalamin daily had 4 times higher B12 levels compared to pre-treatment, reaching therapeutic ranges ( There have also been further studies comparing treatment outcomes from the sublingual route to the more established IM and oral routes

It also helps regulate homocysteine levels, which is important for cardiovascular health