A recent data science evidence-based approach to determine the top ten ingredients in oral skin supplements (from 71,000 dietary ingredients of which 1781 were found to have at least one skin-related publication assessed in human clinical trials) found that collagen had the most published human skin health-related data, followed by specific antioxidants (especially from natural sources or products) [25]
Yang D, Chertov O, Bykovskaia SN, Chen Q, Buffo MJ, Shogan J, Anderson M, Schrder JM, Wang JM, Howard OMZ, Oppenheim JJ: -defensins: linking innate and adaptive immunity through dendritic and T cell CCR6
Pataer A, Chengcheng G, Ruping S, Correa AM, Fang B, Roth JA, Wistuba II, Swisher SG
AAPS PharmSciTech